Pain-free skin patch to automate diabetes management

Dec 27:There is good news for diabetics as researchers have developed a pain-free skin patch containing dissolvable compounds that responds to blood chemistry to manage glucose automatically.
For millions of people with type 2 diabetes, ongoing vigilance over the amount of sugar, or glucose, in their blood is the key to health. A finger prick before mealtimes and maybe an insulin injection is an uncomfortable but necessary routine.
The new study, published online in the journal Nature Communications, showed that the biochemical formula of mineralised compounds in the patch responds to sugar levels for days at a time.
In a proof-of-concept study performed with mice, the researchers showed that the biochemically formulated patch of dissolvable microneedles can make the management of Type-2 diabetes much easier.
"This experimental approach could be a way to take advantage of the fact that persons with Type-2 diabetes can still produce some insulin," said Richard Leapman of National Institute of Biomedical Imaging and Bioengineering (NIBIB), part of National Institutes of Health (NIH), US. "A weekly microneedle patch application would also be less complicated and painful than routines that require frequent blood testing," Leapman said. The base of the experimental patch is material called alginate, a gum-like natural substance extracted from brown algae. It is mixed with therapeutic agents and poured into a microneedle form to make the patch. "Alginate is a pliable material - it is soft, but not too soft," said lead researcher Xiaoyuan (Shawn) Chen of NIBIB. Agencies
Source: Agencies



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