Diet diary: Latest treatment modalities for increasing Celiac and Non-Celiac gluten sensitivity

Jan 11:With a rise in diagnosis of gluten sensitivity and celiac disease, an increasing number of people are adopting a gluten-free lifestyle. The rising incidence of obesity, diabetes, digestive, autoimmune problems and general wellness is also driving a trend towards such lifestyle choices. Therefore, it is not surprising that the sales of gluten-free products has shot up exponentially over the last decade, and as per US data reported by the National Health and Nutrition Examination Survey (NHANES), continues to do so.
The treatment for Celiac disease or Non-Celiac Gluten sensitivities is a lifelong, strict gluten-free diet. As of now, knowledge of grain science and elimination is the only available and accepted treatment. Alternate grains like rice, millets, jowar, bajra, ragi, quinoa, potato and starches are safe options. However, compliance to a gluten-free diet is difficult, especially for adolescents. It is highly burdensome to patients and has its limitations as most of our favourite foods contain gluten. In other words, it is easier said than done in the urban lifestyle. Therefore, new strategies for prevention and treatment modalities, other than following a gluten-free diet, are greatly needed.
Extensive research in this field is being conducted across the world for treatment and prevention. Enzyme treatment and vaccinations are some of the options being assessed. Interesting new areas which are emerging include traditional baking techniques, by longer baking periods, with acidified dough.
Traditional sourdough fermentation for making leavened baked goods, was almost completely replaced by the use of baker's yeast and chemical leavening agents in the last century. Recently, it has been rediscovered by the scientific community. Acidification, protein breakdown and activation of enzymes cause several changes during sourdough fermentation, carried out by lactic acid bacteria and yeasts. These are believed to positively affect the overall quality of the baked goods. In other words gluten protein undergoes degradation through bacteria and enzymes making it easier to tolerate.
In fact, a recent publication in 2011 by Greco et al, in Clinical Gastroenterology and Hepatology Journal, demonstrated that dough baked with such microorganisms contained less than 20 ppm of gluten making it safe for consumption by those who are intolerant. However many more large-scale studies are required to demonstrate the safety and recommendations for such products. Agencies
Source: Agencies



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